Gru and Lucy and their girls—Margo, Edith and Agnes—welcome a new member to the Gru family, Gru Jr., who is intent on tormenting his dad. Gru also faces a new nemesis in Maxime Le Mal and his femme fatale girlfriend Valentina, forcing the family to go on the run.
| Directing | Chris Renaud | Director |
| Directing | Patrick Delage | Co-Director |
| Production | Chris Meledandri | Producer |
| Production | Brett Hoffman | Producer |
| Sound | Pharrell Williams | Songs |
| Sound | Heikki Kossi | Foley Artist |
| Editing | Tiffany Hillkurtz | Editor |
| Production | Helena Muzi Cohen | Production Manager |
| Production | Sandrine Lagareste | Production Supervisor |
| Production | Sean Lawrence | Production Supervisor |
| Production | Charlotte Reichenbach | Production Supervisor |
| Production | Reggie Umali | Production Manager |
| Production | Barbara Harris | Casting |
| Writing | Mike White | Writer |
| Writing | Ken Daurio | Writer |
| Sound | Daniel Laurie | Supervising Sound Editor |
| Sound | Jeremy Bowker | Supervising Sound Editor |
| Sound | Jeremy Bowker | Sound Designer |
| Sound | Gary Rizzo | Sound Re-Recording Mixer |
| Sound | Scott R. Lewis | Sound Re-Recording Mixer |
| Art | Marco Allard | Storyboard Artist |
| Art | David Feiss | Storyboard Artist |
| Art | Chris Allison | Storyboard Artist |
| Art | Serguei Kouchnerov | Storyboard Artist |
| Art | James Wootton | Storyboard Artist |
| Art | Scott Cooper | Storyboard Artist |
| Art | Chris Martin | Storyboard Artist |
| Art | Bryan Cox | Storyboard Artist |
| Art | Glenn McCoy | Storyboard Artist |
| Art | Jim Craig | Storyboard Artist |
| Art | Luis Zamora Pueyo | Storyboard Artist |
| Art | Eric Favela | Storyboard Artist |
| Art | Brad Ableson | Additional Storyboarding |
| Art | Josh Lieberman | Additional Storyboarding |
| Art | Guy Bar'ely | Additional Storyboarding |
| Art | Jim Benton | Additional Storyboarding |
| Art | Kartika Mediani | Additional Storyboarding |
| Art | Jeff Mednikow | Additional Storyboarding |
| Art | Brian Kesinger | Additional Storyboarding |
| Art | Jeffrey R. Ranjo | Additional Storyboarding |
| Art | Peter Rida Michail | Additional Storyboarding |
| Sound | Heitor Pereira | Original Music Composer |
| Production | Robert Taylor | Associate Producer |
| Production | Alexandra Skinazi-Francart | Production Supervisor |
| Writing | Habib Louati | Head of Story |
| Visual Effects | Eric Guillon | Character Designer |
| Visual Effects | Carter Goodrich | Character Designer |
| Visual Effects | Philippe Tilikete | Character Designer |
| Crew | Thomas Berkane | Supervising Animator |
| Crew | Basile Heiderscheid | Supervising Animator |
| Crew | Florent de La Taille | Supervising Animator |
| Crew | Bruno Scheerens | Supervising Animator |
| Crew | Jonathan Duret | Supervising Animator |
| Crew | Antoine Trouillet | Supervising Animator |
| Crew | Nicolas Faucheux | Supervising Animator |
| Crew | Jim Sweeting | Supervising Animator |
| Lighting | Victor Pajot | Lighting Supervisor |
